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Research project

Prof R. Read: MRC Experimental Human Challenge with Genetically Modified Commensals to Investigate Respiratory Tract Mucosal Immunity and Colonisation

Staff

Lead researcher

Professor Robert Read

Chair of Infectious Diseases
Connect with Robert

Email: R.C.Read@soton.ac.uk

Other researchers

Professor Ian Clarke

Professor of Virology

Research interests

  • Transposon mutagenesis of Chlamydia species
  • Cell culture systems and replicons for human noroviruses
Connect with Ian

Email: inc@soton.ac.uk

Professor Saul Faust MBBS, FRCPCH, PhD, FHEA, OBE

Professor Paediatric Immunology & Infect
Connect with Saul

Email: s.faust@soton.ac.uk

Research outputs

Safety, immunogenicity, and reactogenicity of BNT162b2 and mRNA-1273 COVID-19 vaccines given as fourth-dose boosters following two doses of ChAdOx1 nCoV-19 or BNT162b2 and a third dose of BNT162b2 (COV-BOOST): a multicentre, blinded, phase 2, randomised trial
Alasdair P S Munro, Shuo Feng, Leila Janani, Victoria Cornelius, Parvinder K Aley, Gavin Babbage, David Baxter, Marcin Bula, Katrina Cathie, Krishna Chatterjee, Kate Dodd, Yvanne Enever, Ehsaan Qureshi, Anna L Goodman, Christopher A Green, Linda Harndahl, John Haughney, Alexander Hicks, Agatha A van der Klaauw, Nasir Kanji, Vincenzo Libri, Martin J Llewelyn, Alastair C McGregor, Mina Maallah, Angela M Minassian, Patrick Moore, Mehmood Mughal, Yama F Mujadidi, Kyra Holliday, Orod Osanlou, Rostam Osanlou, Daniel R Owens, Mihaela Pacurar, Adrian Palfreeman, Daniel Pan, Tommy Rampling, Karen Regan, Stephen Saich, Tanveer Bawa, Dinesh Saralaya, Sunil Sharma, Ray Sheridan, Emma C Thomson, Shirley Todd, Chris Twelves, Robert C Read, Sue Charlton, Bassam Hallis, Mary Ramsay & Saul N Faust, 2022, The Lancet Infectious Diseases, 22(8), 1131-1141
DOI: 10.1016/S1473-3099(22)00271-7
Type: article
Controlled human infection with Neisseria lactamica in late pregnancy to measure horizontal transmission and microbiome changes in mother-neonate pairs
Anastasia A Theodosiou, Jay R Laver, Adam P Dale, David W Cleary, Christine E Jones & Robert C Read, 2022, BMJ Open, 12(5)
DOI: 10.1136/bmjopen-2021-056081
Type: article
Effect of priming interval on reactogenicity, peak immunological response, and waning after homologous and heterologous COVID-19 vaccine schedules: exploratory analyses of Com-COV, a randomised control trial
Robert H. Shaw, Xinxue Liu, Arabella S.V. Stuart, Melanie Greenland, Parvinder K. Aley, Nick J. Andrews, Saul Faust & Robert Read, 2022, The Lancet Respiratory Medicine, 10(11), 1049-1060
DOI: 10.1016/S2213-2600(22)00163-1
Type: article
Persistence of immunogenicity after seven COVID-19 vaccines given as third dose boosters following two doses of ChAdOx1 nCov-19 or BNT162b2 in the UK: three month analyses of the COV-BOOST trial
Xinxue Liu, Alasdair P S Munro, Shuo Feng, Leila Janani, Parvinder K Aley, Gavin Babbage, David Baxter, Marcin Bula, Katrina Cathie, Krishna Chatterjee, Wanwisa Dejnirattisai, Kate Dodd, Yvanne Enever, Ehsaan Qureshi, Anna L Goodman, Christopher A Green, Linda Harndahl, John Haughney, Alexander Hicks, Agatha A van der Klaauw, Jonathan Kwok, Vincenzo Libri, Martin J Llewelyn, Alastair C McGregor, Angela M Minassian, Patrick Moore, Mehmood Mughal, Yama F Mujadidi, Kyra Holliday, Orod Osanlou, Rostam Osanlou, Daniel R Owens, Mihaela Pacurar, Adrian Palfreeman, Daniel Pan, Tommy Rampling, Karen Regan, Stephen Saich, Teona Serafimova, Dinesh Saralaya, Gavin R Screaton, Sunil Sharma, Ray Sheridan, Ann Sturdy, Piyada Supasa, Emma C Thomson, Shirley Todd, Chris Twelves, Robert C Read & Saul N Faust, 2022, Journal of Infection, 84(6), 795-813
DOI: 10.1016/j.jinf.2022.04.018
Type: article
Antibiotics for lower respiratory tract infection in children presenting in primary care (ARTIC-PC): the predictive value of molecular testing
Paul Little, Robert C. Read, Taeko Becque, Nick A. Francis, Alastair D. Hay, Beth Stuart, Gilly O'Reilly, Natalie Thompson, Kerenza Hood, Saul Faust, Kay Wang, Michael Moore & Theo Verheij, 2022, Clinical Microbiology and Infection, 28(9), 1238-1244
DOI: 10.1016/j.cmi.2022.02.033
Type: article