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Research project

Establishment of a National Network on Musculoskeletal Ageing

Staff

Lead researcher

Professor Cyrus Cooper

Prof Rheumatology Clinical Epidemiology

Research interests

  • Key research contributions have been:
  • discovery of the developmental influences which contribute to the risk of osteoporosis and hip fracture in late adulthood
  • demonstration that maternal vitamin D insufficiency is associated with sub-optimal bone mineral accrual in childhood
Connect with Cyrus

Email: cc@mrc.soton.ac.uk

Other researchers

Professor Nicholas Harvey

Director/Professor

Research interests

  • Lifecourse epidemiology of osteoporosis and fragility fractures
  • Understanding mechanism and development of novel interventions across lifecourse to prevent fragility fractures
Connect with Nicholas

Email: nch@mrc.soton.ac.uk

Collaborating research institutes, centres and groups

Interdisciplinary Musculoskeletal Health

The University hosts a substantial interdisciplinary community of researchers working to transform musculoskeletal health across the life course.

Research outputs

Impact of the COVID-19 pandemic on community-dwelling older adults
Ilse Bloom, Jean Zhang, Julia Hammond, Gregorio Bevilacqua, Wendy Lawrence, Kate A Ward, Cyrus Cooper & Elaine M Dennison, 2022, PLoS ONE, 17(10 October)
DOI: 10.1371/journal.pone.0275486
Type: article
Osteoporosis treatment in Austria-assessment of FRAX-based intervention thresholds for high and very high fracture risk
Hans P. Dimai, Helena Johansson, Nicholas C. Harvey, Mattias Lorentzon, Enwu Liu, Liesbeth Vandenput, Astrid Fahrleitner-Pammer, Peter Pietschmann, Christian Muschitz, Eugene V. McCloskey & John A. Kanis, 2022, Archives of Osteoporosis, 17(1)
DOI: 10.1007/s11657-022-01175-w
Type: article
Novel formulations of oral bisphosphonates in the treatment of osteoporosis
Nicholas Fuggle, Nasser Al-Daghri, Olivier Bock, Jaime Branco, Olivier Bruyère, Enrique Casado, Etienne Cavalier, Bernard Cortet, Maarten de Wit, Andrea Giusti, Philippe Halbout, Nicholas C Harvey, Mickaël Hiligsmann, Jean-Marc Kaufman, Andreas Kurth, Stefania Maggi, Radmila Matijevic, Salvatore Minisola, Santiago Palacios, Régis Pierre Radermecker, Friederike Thomasius, Sansin Tuzun, Nicola Veronese, John A Kanis, Jean-Yves Reginster, René Rizzoli & Cyrus Cooper, 2022, Aging Clinical and Experimental Research, 34(11), 2625-2634
DOI: 10.1007/s40520-022-02272-z
Type: review
The need to distinguish intervention thresholds and diagnostic thresholds in the management of osteoporosis
John A Kanis, Eugene V. McCloskey, Nicholas C Harvey, Cyrus Cooper, Rene Rizzoli, Bess Dawson-Hughes, Stefania Maggi & Jean-Yves Reginster, 2022, Osteoporosis International, 34(1), 1-9
DOI: 10.1007/s00198-022-06567-9
Type: article
General comorbidity indicators contribute to fracture risk independent of FRAX
Gregory A Kline, Suzanne N Morin, Lisa M Lix, Eugene V McCloskey, Helena Johansson, Nicholas C. Harvey, John A Kanis & William D Leslie, 2022, Journal of Clinical Endocrinology & Metabolism
DOI: 10.1210/clinem/dgac582
Type: article